Anti TNF-alfa como opción terapéutica en Pacientes con Superposición de Artritis Reumatoide, Lupus Eritematoso Sistémico y Hepatitis C

Cesar Ricardo Ortega Espinosa, Lina Maria Saldarriaga Rivera, Luis Alberto Delgado Quiroz, Blanca Elena Rios Gomes Bica

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Resumen

La incidencia de infección crónica por el virus de hepatitis C (VHC) en un paciente con enfermedad reumática es un desafío diagnóstico y terapéutico, ya que los medicamentos utilizados en el tratamiento de la artritis reumatoide (AR) y del lupus eritematoso sistémico (LES) son hepatotóxicos. Describimos el caso de una paciente de sexo femenino, con superposición de AR y LES con serología positiva para hepatitis C, quien recibió tratamiento con interferón alfa sin respuesta y en presencia de actividad de la enfermedad reumática fue refractaria al tratamiento, siendo utilizado Anti-TNF etanercept con resolución de la sintomatología.

Palabras clave

Artritis Reumatoide; Lupus Eritematoso sistémico; Hepatitis C; Anti-TNF alfa

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