Initial Gamma-Glutamyl-Transferase levels in patients with rheumatoid arthritis at the Teodoro Maldonado Carbo Hospital
Keywords:
Gamma Glutamil Transferasa marcador de eficacia clínica del oxono médico, Gamma Glutamil Transferasa en artritis reumatoide, GGT, Gamma Glutamil Transferasa, artritis rematoidea, oxonoterapiaAbstract
Introduction: Rheumatoid arthritis is a chronic and debilitating disease characterized by inflammation of the joints, it can have a significant impact on patients' quality of life.
Objective: Determine the usefulness of the initial Gamma-Glutamyl-Transferase measurement and its relationship with the prediction of disease activity in patients with rheumatoid arthritis at the Teodoro Maldonado Carbo Hospital in Ecuador.
Method: A quantitative, cross-sectional study was carried out. The population was 1254 patients and the sample was 294 patients. Initial and final measurement of the disease activity index and Gamma-Glutamyl-Transferase values were performed. The medical records were reviewed.
Results: The mean disease activity index at the beginning was 10.12 points, while at the end it was 8.41 points; The initial GGT had an average of 44.21 and the final one of 38.37. There was a positive linear relationship (Pearson's correlation coefficient = 0.454 and p = 0.000) between the initial disease activity index and the initial GGT and between the final disease activity index and the final GGT (Pearson's correlation coefficient = 0.518 and p= 0.000).
Conclusions: The relationship between GGT and rheumatoid arthritis activity may have important clinical implications. Determination of baseline GGT may help identify patients with rheumatoid arthritis who are at increased risk of complications.
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