Índice neutrófilo/linfocitos en pacientes con enfermedades reumáticas autoinmunes crónicas
Keywords:
Neutrophil-to-lymphocyte ratio, autoimmune rheumatic diseases, systemic lupus erythematosus, rheumatoid arthritis, biomarkerAbstract
Las enfermedades reumáticas autoinmunes crónicas son un conjunto de trastornos donde el sistema inmunológico ataca estructuras del propio cuerpo del paciente, lo cual le provoca daños generalizados en tejidos y órganos, lo que a su vez va asociado con mayor morbilidad y mortalidad. Sus manifestaciones clínicas pueden variar significativamente entre los individuos, lo que conlleva a que tanto el diagnóstico como el tratamiento se compliquen.
Entre las principales enfermedades reumáticas autoinmunes crónicas se encuentra la artritis reumatoide que es una enfermedad inflamatoria crónica que afecta principalmente a las articulaciones y cuyos síntomas fundamentales son el dolor, la rigidez matutina y la inflamación en las articulaciones; si no se trata adecuadamente pueden aparecer deformidades permanentes.
También está el lupus eritematoso sistémico que puede afectar cualquier órgano y sistema; se caracteriza por un conjunto de síntomas variados que van desde erupciones cutáneas hasta problemas renales graves afectando fundamentalmente a mujeres jóvenes.
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Copyright (c) 2025 Roger Armando Somoza Delgado, José Pedro Martínez Larrarte , Silvia María Pozo Abreu, Ana Marta López Mantecón, Eneida Barrios Lamoth
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