Epigenética y enfermedades autoinmunes sistémicas

Ana María Torres Lima; Ana Yolanda Rodríguez Torres

Epigenética y enfermedades autoinmunes sistémicas

Ana María Torres Lima, Ana Yolanda Rodríguez Torres

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Resumen

La epigenética, como ciencia que estudia la modificaciones heredables en la función del genoma que se realizan sin cambios en la secuencia del ADN, está atrayendo una atención creciente entre la comunidad científica, por su contribución en la patogenia de un grupo numeroso de enfermedades, en sus enfoques terapéuticos e incluso en la prevención de las mismas. Las enfermedades autoinmunes sistémicas tienen una etipatogenia multifactorial compleja y en los últimos años las evidencias tanto clínicas, como experimentales, de la influencia que ejercen los cambios en el epigenoma, en estas entidades clínicas, son numerosas y pretendemos abordarlas en esta serie de artículos de revisión.

Palabras clave

epigenética; enfermedades autoinmunes; enfermedades sistémicas

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