Gout Arthritis. Ten years of follow up

Yanelis Vizcaino Luna, Witjal Manuel Bermúdez Marrero, William Alejandro Bermúdez Marrero, Jorge Luis Egües Mesa, Tamara Cárdenas Domínguez, Eric Prendes García

Texto completo:

PDF (English) HTML (English)


Introduction: Gouty arthritis is a persistent metabolic disease that produces an increase of the circulating uric acid, with the resulting deposit of monosodic urate crystals in the tissues.
: To characterize patients with gouty arthritis clinically and epidemiologically.
: A descriptive investigation of 72 patients with a diagnosis of gouty arthritis, assisted at Arnaldo Milián Castro Clinical Surgical University Hospital was carried out from January 2008 to December 2017.
: Patients between 40 and 49 years of age were the most representative group with a highest incidence in not white patients and the male sex. Obesity and hypertension prevailed as previous personal antecedents. Alcohol intake was the most represented toxic habit.  A crisis of inflammation of the big toe was the more frequent starting manifestation. Swelling of soft tissues was the main radiologic alteration.
Conclusion: Gouty arthritis is present with a highest frequency in the male sex with a peak of incidence in the fourth decade of life. It is associated to bad diet habits and alcohol intake that could cause joint damage.

Palabras clave

gouty arthritis; gout; uric acid; hyperuricaemia


Singh JA, Yu S. Gout-related inpatient utilization: a study of predictors of outcomes and time trends. Arthritis Res Ther. 2015;18(1):57.

Jeyaruban A, Soden M, Larkins S. General practitioners’ perspectives on the management of gout: a qualitative study. Postgrad Med J. 2016;92(1092):603-7.

Humphrey C, Hulme R, Dalbeth N, Gow P, Arroll B, Lindsay K. A qualitative study to explore health professionals’ experience of treating gout: understanding perceived barriers to effective gout management. J Prim Health Care. 2016;8(2):149-56.

Chandratre P, Mallen CD, Roddy E, Liddle J, Richardson J. “You want to get on with the rest of your life”: a qualitative study of health-related quality of life in gout. Clin Rheumatol. 2016;35(5):1197-205.

Pérez Ruíz F. Gota. En: Sociedad Española de Reumatología. Manual SER de las Enfermedades Reumáticas. 6ta ed. Barcelona: Ed. Elsevier; 2014. p. 489-495.

Arthritis Research. Can Epigenetics Switch Off Gout? [Internet]. 2017 Jun [cited 2017 Sep 5]. Available from: https://curearthritis.org/epigenetics-gout/

Prior JA, Mallen CD, Chandratre P, Muller S, Richardson J, Roddy E. Gout characteristics associate with depression, but not anxiety, in primary care: baseline findings from a prospective cohort study. Joint Bone Spine. 2016;83(5):553-8.

Singh JA. Facilitators and barriers to adherence to urate-lowering therapy in African-Americans with gout: a qualitative study. Arthritis Res Ther. 2014;16(2):R82.

Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M. Comorbidities in patients with gout prior to and following diagnosis: case-control study. Ann Rheum Dis. 2016;75(1):210-7.

Jordan KM, Cameron JS, Snaith M, Zhang W, Doherty M, Seckl J, et al. British Society for Rheumatology and British Health Professionals in Rheumatology. Rheumatology. 2012;46:1372-4.

SchumacherJr HR, Edwards LN, Perez-Ruiz F, Becker M, Chen LX, Furst DE, et al. Outcome measures for acute and chronic gout J Rheumatol. 2013;32:2452-5.

Singh JA, Bharat A, Khanna D, Aquino-Beaton C, Persselin JE, Duffy E, Elashoff D, Khanna PP. Racial differences in health-related quality of life and functional ability in patients with gout. Rheumatology (Oxford). 2017;56(1):103-12.

Singh JA. The impact of gout on patient’s lives: a study of African-American and Caucasian men and women with gout. Arthritis Res Ther. 2014;16(3):R132.

Martínez Larrarte JP. Caracterización de los pacientes con gota atendidos en la consulta externa del hospital regional de Malabo. Rev Cubana de Reumatolo. 2010;12(16):[aprox. 8 p.]

Monu J, Pope T. Gout: a clinical and radiological review. Radiol Clin North Am. 2013;42(1).

Pinto J, Mora G, Fernández-Ávila D, Gutiérrez J, Díaz M, Grupo Javeriana de Investigaciones en Enfermedades Reumáticas. Tocilizumab en pacientes con gota tofácea severa en pacientes refractarios a tratamientos. Unidad de Reumatología. Departamento de Medicina Interna. Hospital Universitario San Iguala. Pontificia Universidad Javeriana. Bogotá. Colombia. Reumatol Clin [Internet]. 2013 [citado 5 Sep 2017];9(3):178- 80. Available from: http://www.Reumatologíaclínica.org

Singh JA. Gout and comorbidity: a nominal group study of people with gout. Arthritis Research & Therapy [Internet]. 2017 [cited 2019 Jan 3];19(1):204. Available from: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-017-1416-8

Sicras-Mainar A. Álvarez RV. Galera Llorca J. Granell Villalón M. Navarro-Artieda R. Estudio de pacientes con gota: características clínicas en los últimos 2 años de seguimiento. Gaceta Médica de México. 2012;148:448-56. Available from: http://www.medigraphic.com/pdfs/gaceta/gm-2012/gm125d.pdf

Hospital General de Vancouver Canadá y Harvard Medical School, de Boston EEUU. [Internet]. 2012 [cited 2013 Jan 7]. Available from: http://www.dietas.com/articulos/los-refrescos-azucarados-contribuyen-a-la-gota-segun-estudio.asp

Liddle J, Roddy E, Mallen CD, Hider SL, Prinjha S, Ziebland S, Richardson JC. Mapping patients’ experiences from initial symptoms to gout diagnosis: a qualitative exploration. BMJ Open. 2015;5(9):e008323.

Artritis Foundation. What is gout [Internet]. 2015 [cited 2017 Mar 10]. Available from: https://www.arthritis.org/about-arthritis/types/gout/what-is-gout.php

González-Rozas M. Prieto de Paula JM, Franco Hidalgo S, López Pedreira MR. Gota tofácea crónica. Semergen. 2013;39(6):e29-e34. Available from: www.elsevier.es/semergen

Puig J, Torres R, Mateos F, Ramos T, Arcas J, Buño A, et al. The spectrum of Hypoxantine-guanine phosphoribosyl/transferase (HPRT) deficiency. Clinical experience based on 22 patients from 18 spanish families. Medicine (Baltimore). 2012;84:102-12.

Kingsbury SR, Conaghan PG, McDermott MF. The role of the NLRP3 inflammasome in gout. J Inflamm Res. 2011;4:39-49.

Arthritis Foundation. [Internet]. 2012 [citado 2019 Jan 7]. Available from: http://www.arthritis.org/espanol/er--gota-obesidad.php

Enlaces refback

  • No hay ningún enlace refback.

Copyright (c) 2019 Yanelis Vizcaino Luna, Witjal Manuel Bermúdez Marrero

Licencia de Creative Commons
Esta obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial 4.0 Internacional.