Prescription of gastric protectors in rheumatological patients: Analysis from a gastroenterology outpatient clinic
Keywords:
nonsteroidal anti-inflammatory drugs, gastric protectors, variability of the safety profile, rheumatological patients, external consultation, prescription, gastroenterological perspectiveAbstract
Introduction: Nonsteroidal anti-inflammatory drugs are the most prescribed medications by rheumatologists and traumatologists. However, despite having similar efficacy in controlling inflammation and pain, the different available nonsteroidal anti-inflammatory drugs show variability in their safety profile.
Objective: To provide an overview of the prescription of gastric protectors in rheumatological patients, in two hospital centers, from a gastroenterological perspective.
Methods: The research is part of the quantitative paradigm with an observational study. Two groups of patients were formed, one of them from hospital A and the second group belonged to hospital B.
Discussion: Gastroprotectors have become the drugs in greatest demand in community pharmacies in Ecuador, the most prescribed being Proton Pump Inhibitors (IBPS) and, to a lesser extent, H2 antihistamines (anti-H2). Regarding the most frequently prescribed gastroprotectors, according to our study, these values could be due to the availability and costs of famotidine and omeprazole compared to other drugs with proven effectiveness, such as ansoprazol, pantoprazole, rabeprazole and ranitidine.
Conclusions: In recent years, the use of gastroprotective drugs in Latin America has undergone significant development, with the observance of clinical case management norms and guidelines that offer important recommendations in this regard. Therefore, from a gastroenterological perspective, to be successful, it is essential to seek knowledge of these contributions and scientific evidence.
Downloads
References
López Alama O M. Relación de AINES con sintomatología digestiva alta en pacientes de consultorio gastroenterología, Hospital II Jorge Reátegui. Repositorio Upao Edu [Internet]. 2020 [Acceso: 16/10/2021]julio-diciembre. Disponible en: http://repositorio.upao.edu.pe/handle/20.500.12759/6088
Batlouni M. Antiinflamatorios no esteroides: efectos cardiovasculares, cerebrovasculares y renales. Arquivos Brasileiros de Cardiologia [Internet]. 2010;94,556-63.
Prieto JM. Antiinflamatorios No Esteroideos (AINEs). Cient Dent [Internet]. 2007 [Acceso: 16/10/2021]; 4(3):203-212. Disponible en: https://www.academia.edu/download/49673627/3_AINES_DONDE_ESTAMOS_Y_HACIA_DONDE_NOS_DIRIGIMOS.pdf
Velasco-Zamora JA, Gómez-Reyes E, Uscanga L. Are the clinical guideline recommendations on gastroprotection being followed? A review in patients taking nonsteroidal anti-inflammatory drugs. Revista de Gastroenterología de México (English Edition) [Internet]. 2016 [Acceso: 16/10/2021];81(3):121-5. Disponible en: https://www.sciencedirect.com/science/article/pii/S2255534X16300366
Sostres C, Lanas Á. Prescripción apropiada, adherencia y seguridad de los antiinflamatorios no esteroideos. Medicina Clínica [Internet]. 2016 [Acceso: 16/10/2021]; 146(6), 267-272. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0025775315005928
Salvatierra Laytén G, de la Cruz Romero L, Paulino Merino M, Vidal Vidal V, Rivera Dávila C, Cano Chuquilin A, et al. Hemorragia digestiva alta no variceal asociada al uso del antiinflamatorios no esteroideos en Lima Metropolitana. Revista de Gastroenterología del Perú [Internet]. 2006 [Acceso: 16/10/2021];26(1):13-20. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1022-51292006000100002&lng=es&tlng=es
de Crohn E, Ulcerosa C. Enfermedad Inflamatoria Intestinal al Día [Internet]. 2016 [Acceso: 16/10/2021]. Disponible en: http://fisiogenomica.com/assets/Blog/pdf/gonzlezlama2016.pdf
González Lama Y, et al. Recomendaciones del Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU) sobre el tratamiento de pacientes con espondiloartritis asociada a enfermedad inflamatoria intestinal. Enferm inflam intest dia [Internet]. 2016. [Acceso: 16/10/2021] Disponible en: http://dx.doi.org/10.1016/j.eii.2016.09.002
Urrutia LAM, Laytén GS, Velarde OF. Perfil del consumidor de antiinflamatorios no esteroideos en Chiclayo y Cajamarca, Perú. Acta Médica Peruana. 2008;25(4):216-9.
Lanas A, Martín Mola E, Ponce J, Navarro F, Piqué JM, Blanco FJ. Estrategia clínica para la prevención de los efectos adversos sobre el tracto digestivo de los antiinflamatorios no esteroideos. Recomendaciones de la Asociación Española de Gastroenterología y de la Sociedad Española de Reumatología. Gastroenterol Hepatol, 2003;26(8):487-504.
Velasco Zamora JA, Gómez Reyes E, Uscanga L. Are the clinical guideline recommendations on gastroprotection being followed? A review in patients taking nonsteroidal anti-inflammatory drugs. Revista de Gastroenterología de México. 2016;81(3):121-5.
Badia JG, Lozano AP, Ramos AC. Protección gástrica en el tratamiento con AINE. Atención primaria: Publicación oficial de la Sociedad Española de Familia y Comunitaria [Internet].1997[Acceso: 16/10/2021];19(4),207-10. Disponible en: https://www.elsevier.es/es-revista-atencion-primaria-27-articulo-proteccion-gastrica-el-tratamiento-con-14486
Castellanos Gutiérrez M, Solis Cartas U, Faure Bermúdez A, Villaurrutia Velazco YC. Gastropatía por antinflamatorios no esteroideos en pacientes con enfermedades reumáticas. Rev Cuba Reumatol [Internet]. 2014 [Acceso: 16/10/2021];16( Suppl 1): 356-64. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1817-59962014000400003&lng=es
Barbón Pérez OG, López Granda CL. Formación permanente, superación profesional y profesionalización pedagógica. Tres procesos de carácter continuo y necesario impacto social. Rev Cuba Reumatol [Internet]. 2014 [Acceso: 16/10/2021]; 16(1):59-62. Disponible en: http://scielo.sld.cu/scielo.php?pid=S1817-59962014000100012&script=sci_arttext&tlng=en
Hermida Ameijeiras Á, Cabana González B, Lorenzo Zúñiga V. Prevalencia de prescripción: indicación de protectores gástricos en pacientes hospitalizados. Gaceta Sanitaria [Internet]. 2007 [Acceso: 16/10/2021]; 21(5):412-5. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0213-91112007000500010
Giovanella L, Vega R, Tejerina Silva H, Acosta Ramirez N, Parada Lezcano M, Ríos G, et al. ¿Es la atención primaria de salud integral parte de la respuesta a la pandemia de Covid-19 en Latinoamérica? Trabalho, Educação e Saúde. [Internet]. 2020 [Acceso: 16/10/2021]; 19. Disponible en: https://www.scielo.br/j/tes/a/CJX9Rs5gSBJmsMrfwhkdJrL/?lang=es&format=html
de Aparicio, CXP. Salud laboral frente a la pandemia del COVID-19 en Ecuador. MediSur. 2020;18(3):507-11.
Guacho Paca DF. Análisis de la dispensación de gastroprotectores en tres farmacias comunitarias de Riobamba-Ecuador Internet]. 2019 [Acceso: 16/10/2021] (Bachelor's thesis, Escuela Superior Politécnica de Chimborazo). Disponible en: http://dspace.espoch.edu.ec/bitstream/123456789/10807/1/56T00869.pdf
Downloads
Published
How to Cite
Issue
Section
License
Warning of rights of author
The authors that publish in this journal agree with the following terms:
The authors conserve the rights of author and concede to the journal the right of the first publication, fulfilling with the license Creative Commons Attribution License that allows to others share the work with recognition of the authorship of their articles, and the initial publication in this journal.
The authors can establish separately additional agreements for the no exclusive distribution of the version of the work published in the journal (for example, situate it in an institutional repository, in a personal blog or publish it partial or totally in a book), with a recognition of their initial publication in this journal.
To be able to send the manuscript or part of him passed three months of published, for his evaluation to other publishers, identifying it or not with the same title; whenever allusion is made to our journale and know it the new publisher.
The publishing committee of the Cuban Journal of Rheumatology authorizes to other publishers, to reproduce the articles published in our magazine, whenever it indicate the origin of the same.
The authors should send a document in Office Word application format through the electronic address of the magazine with a similar format to that we include next:
---------------------------------------------------------------------------------------------------------------------
Statement of authorship and cede of articles for the publication of the scientific work in the Cuban Journal of Rheumatology
Date:
Those who subscribe certify that are the authors of the work:
Of this form communicate the originality of our article clearing that the concepts and knowledges of other authors that have included in the text of the article, have been quoted properly in the bibliography.
We do proof besides that the article in question is original and has not been published, total neither partially, in another journal.
To be approved for his publication in the Cuban Journal of Rheumatology, do secession of the rights of publication to the same one through the method that realizes it usually.
In front of any catchword that exist by the article that send to evaluate, relieve of of the responsibility to the Cuban Journal of Rheumatology holding us responsible with all the difficulties that can berelated by any situation.
We include to continuation the name and the signature of all authors and collaborators of this article.
Name: Signature:
