Clinical epidemiologic patients' characterization with systemic sclerosis in Holguín

Authors

  • Jorge Alexander Ríos-Flórez Universidade Federal do Rio Grande do Norte. Grupo de Estudio e Investigación en Neurociencias, http://orcid.org/0000-0002-8367-8225
  • Carolina Escudero-Corrales Universidad Pontificia Bolivariana. Grupo de Estudio e Investigación en Neurociencias Hippocampus..
  • Claudia Rocío López-Gutiérrez Universidad Católica Luis Amigó. Grupo de Estudio e Investigación en Neurociencias Hippocampus.

Keywords:

Anxiety, Autoimmune, Cognition, Depression, Systemic Lupus Erythematosus, SLE, Neuropsychology

Abstract

 The objective of this research was to determine the neuropsychological and neuropsychiatric sequelae associated with Systemic Lupus Erythematosus. A comparative-correlational analysis design was proposed, in a study of 68 individuals, a clinical group consisted of 34 patients diagnosed with Systemic Lupus Erythematosus and the control with 34 people in an even condition to each patient, in relation to age, gender and degree. The entire profile of neurocognitive functioning and emotional and behavioral psychiatric symptoms associated with depression and anxiety were analyzed, correlated to variables such as age, time of onset development of the symptoms of Systemic Lupus Erythematosus and the time of diagnosis after the onset of symptoms. The results suggest patterns of neuropsychiatric pathology characteristic of depression and anxiety disorders such as comorbidity and not as a sequel to Systemic Lupus Erythematosus. No difficulties in recognizing complex emotions. With short and long term verbal memory deficit for extensive contents, short and long term visual memory failures. They did not show commitment in processes of comprehension or verbal fluency. With alteration in executive functions, mainly monitoring and regulation of behavior. Failures in attentional processes in patients with depressive symptoms; Those who have anxiety have altered the speed of information processing. The Systemic Lupus Erythematosus as autoimmune pathology functionally affects not only the quality of life of the patient and their daily life at motor level, it also entails a neuropsychological deterioration profile that is associated to the moment of symptom manifestation and to the time that has elapsed until the diagnosis was established, from which the intensity and evolution of neurofunctional deterioration derive.

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Author Biographies

Jorge Alexander Ríos-Flórez, Universidade Federal do Rio Grande do Norte. Grupo de Estudio e Investigación en Neurociencias,

Investigador-Docente, Director del Grupo de Estudio e Investigación en Neurociencias Hippocampus; Magíster Neuropsicólogo Clínico; Doctorando en Psicobiología.

Carolina Escudero-Corrales, Universidad Pontificia Bolivariana. Grupo de Estudio e Investigación en Neurociencias Hippocampus..

Psicóloga investigadora, Coordinadora de la línea de investigación “Trastornos Neurológicos en la adultez” y de la línea de estudio “Neurociencia computacional” del Grupo de Estudio e Investigación en Neurociencias HIPPOCAMPUS.

Claudia Rocío López-Gutiérrez, Universidad Católica Luis Amigó. Grupo de Estudio e Investigación en Neurociencias Hippocampus.

Psicóloga investigadora, Coordinadora de la Línea de investigación en “Síndromes Neurológicos en la infancia” y la Línea de estudio en “Neurociencia afectiva y emocional” del Grupo de Estudio e Investigación en Neurociencias.

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Published

2018-01-31

How to Cite

1.
Ríos-Flórez JA, Escudero-Corrales C, López-Gutiérrez CR. Clinical epidemiologic patients’ characterization with systemic sclerosis in Holguín. Rev. cuba. de Reumatol. [Internet]. 2018 Jan. 31 [cited 2025 Dec. 24];20(1):e11. Available from: https://revreumatologia.sld.cu/index.php/reumatologia/article/view/591

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