Tumor of giant cells of the femur
Keywords:
giant cell tumor of boneAbstract
The giant cell tumor of bone is a rare benign tumor with a locally aggressive behavior. It predominates in women and usually occurs in the epiphysis and metaphysis of long bones. To present a patient with a tumor lesion left knee and thigh two years of evolution, also noted the diagnostic characteristics of this tumor while recent imaging methods are reviewed for confirmation. 19-year-old male who began with pain, increased volume of the knee and left thigh, accompanied by functional impotensia. clinical, radiological and histological findings were reported. Because of the delay between the onset of symptoms and diagnosis surgical treatment of the affected limb (amputation) was performed. After ten months of observation there have been no recurrences or metastases. The giant cell tumor of bone is a rare tumor with good prognosis but can recur and metastasize when it becomes malignant. The possibility of transformation in sarcoma requires periodic study and observation. The time for diagnosis is essential and should think of this tumor in case of lytic bone lesions reported by imaging.
Downloads
References
Jaffé H, Lichtenstein S, Portis R. Giant cell Tumor of bone. Arch Pathol. 1940; 30: 993-1031.
Pila Pérez R, Pila Pelaéz R, Rosales Torres P, Holguín Prieto V. Tumor de células gigantes de hueso y manifestaciones paraneoplásicas. Comunicación de un caso. Mapfre Medicina. 2007;18(1):36-41.
Lopez-Pousa A, Brotó JM, Garrido T, Vázquez. Giant cell tumor of bone: new treatments in development; Clin Transl Oncol. 2015;17:419-30.
Enneking W. Musculoskeletal Tumor surgery. New York: Ed Churchill; Livingstone, 1983: 87-8.
Vaidya K, Sarode GS, Sarode SC, Majumdar B, Patil S. Peripheral giant cell granuloma recurring as an exclusively intraosseous lesion: An unusual clinical presentation. Clin. Pract. 8(1):1023-2018.
Aarcón A, Muñoz R M, Schetner K, Ulloa MC. Peripheral giant cell granuloma and hyperparathyroidism. Case report. Int. J. Odontostomat. 2019;13(3):266-70.
Consoli NR, Berardi AG, Pasquale NV, Pesce MA, De Franceschi C. Granuloma central de células gigantes. Caso clínico y tratamiento quirúrgico. Rev Asoc Odontol Argent. 2018;106:93-7.
Loquercio G, Di Costanzo G, Fazioli F, Gallo M, De Chiara A, Lervolino V, et al. Autologous platelet gel improves bone reconstruction of large defects in patients with bone giant cell tumors. In Vivo. Sept-Oct. 2015;29(5):533-40.
Rajani R, Schaefer L, Scarborough MT, Gibbs CP. Giant cell tumors of the foot and ankle bones: high recurrence rates after surgical treatment. J Foot Ankle Surg. 2015;54(6):1141-5
Wysocki RW, Soni E, Virkus WW, Scarborough MT, Leurgans SE, Gitelis S. Is intralesional treatment of giant cell tumor of the distal radius comparable to resection with respect to local control and functional outcome? Clin Orthop Relat Res. 2015;473(2):706-15.
Cheng DD, Hu T, Zhang HZ, Huang J, Yang QC. Factors affecting the recurrence of giant cell tumor of bone after surgery: A clinicopathological study of 80 cases from a single center. Cell Physiol Biochem. 2015;36(5):1961-70.
Niu X, Xu H, Inwards CY, Li Y, Ding Y, Letson GD, et al. Primary Bone Tumors: Epidemiologic comparison of 9 200 patients treated at Beijing Ji Shui Tan Hospital, Beijing, China, with 10 165 patients at MayoClinic, Rochester, Minnesota. Arch Pathol Lab Med. 2015;139(9):1149-55.
Chan CM, Adler Z, Reith JD, Gibbs CP. Risk factors for pulmonary metastases from giant cell tumor of bone. J Bone Joint Surg Am. 2015;97(5):420-8.
Downloads
Published
How to Cite
Issue
Section
License
Warning of rights of author
The authors that publish in this journal agree with the following terms:
The authors conserve the rights of author and concede to the journal the right of the first publication, fulfilling with the license Creative Commons Attribution License that allows to others share the work with recognition of the authorship of their articles, and the initial publication in this journal.
The authors can establish separately additional agreements for the no exclusive distribution of the version of the work published in the journal (for example, situate it in an institutional repository, in a personal blog or publish it partial or totally in a book), with a recognition of their initial publication in this journal.
To be able to send the manuscript or part of him passed three months of published, for his evaluation to other publishers, identifying it or not with the same title; whenever allusion is made to our journale and know it the new publisher.
The publishing committee of the Cuban Journal of Rheumatology authorizes to other publishers, to reproduce the articles published in our magazine, whenever it indicate the origin of the same.
The authors should send a document in Office Word application format through the electronic address of the magazine with a similar format to that we include next:
---------------------------------------------------------------------------------------------------------------------
Statement of authorship and cede of articles for the publication of the scientific work in the Cuban Journal of Rheumatology
Date:
Those who subscribe certify that are the authors of the work:
Of this form communicate the originality of our article clearing that the concepts and knowledges of other authors that have included in the text of the article, have been quoted properly in the bibliography.
We do proof besides that the article in question is original and has not been published, total neither partially, in another journal.
To be approved for his publication in the Cuban Journal of Rheumatology, do secession of the rights of publication to the same one through the method that realizes it usually.
In front of any catchword that exist by the article that send to evaluate, relieve of of the responsibility to the Cuban Journal of Rheumatology holding us responsible with all the difficulties that can berelated by any situation.
We include to continuation the name and the signature of all authors and collaborators of this article.
Name: Signature: