Tomography by emission of positrons in the diagnosis of sarcoidosis and Löfgren's syndrome

Authors

  • Gil Alberto Reyes Llerena Servicio de reumatología. Centro de investigaciones médico quirúrgicas CIMEQ. Universidad de Ciencias Médicas de La Habana
  • Rafael Frías Pita
  • Pablo Mateo Díaz
  • José Antonio Martínez Quesada
  • Daril Gutiérrez. Rodríguez Universidad de Ciencias Médicas de La Habana. Centro de Investigaciones Médico Quirúrgicas. La Habana
  • Nelson Rodríguez Mesa Universidad de Ciencias Médicas de La Habana. Centro de Investigaciones Médico Quirúrgicas. La Habana
  • Jesús Piñera Molina Universidad de Ciencias Médicas de La Habana. Centro de Investigaciones Médico Quirúrgicas. La Habana
  • Carlos Alberto Herrera Pérez Universidad de Ciencias Médicas de La Habana. Centro de Investigaciones Médico Quirúrgicas. La Habana

Keywords:

sarcoidosis, bilateral hilar lymphadenopathy, erythema nodosum, Löfgren's syndrome, PET-CT

Abstract

Sarcoidosis is a multisystemic, non-caseating granulomatous disease of unknown cause that involves the lung and the mediastinal lymph nodes in between 90% and 95% of cases. It can also affect other organs, such as the salivary glands, skin, eyes, liver, spleen, heart, bones, and central nervous system. Thoracic involvement represents the main cause of morbidity and mortality in patients with this entity, which occurs in about 10 / 100,000 people a year. Our study aimed to present a 45-year-old patient treated for presenting clinical, paraclinical and radiological manifestations that allow the diagnosis of an acute form of sarcoidosis to be established without confirming by histological study. Its clinical form of expression showed the presence of Löfgren's syndrome with bilateral mediastinal widening due to hilar lymphadenopathy, febrile syndrome, erythema nodosum, and acute arthritis in the lower limbs, which 20-30% of patients with sarcoidosis develop. A positron emission tomography scan was performed and its results offered us diagnostic elements typical of a pulmonary inflammatory process far from the characteristics of a malignant neoplastic process.

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Author Biography

Gil Alberto Reyes Llerena, Servicio de reumatología. Centro de investigaciones médico quirúrgicas CIMEQ. Universidad de Ciencias Médicas de La Habana

Dr.C Especialista de 1er Grado en Medicina Interna y 2do Grado en Reumatología Profesor e investigador titular

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Published

2020-12-15

How to Cite

1.
Reyes Llerena GA, Frías Pita R, Mateo Díaz P, Martínez Quesada JA, Gutiérrez. Rodríguez D, Rodríguez Mesa N, et al. Tomography by emission of positrons in the diagnosis of sarcoidosis and Löfgren’s syndrome. Rev. cuba. de Reumatol. [Internet]. 2020 Dec. 15 [cited 2025 Feb. 5];22(4 Extra.):e180. Available from: https://revreumatologia.sld.cu/index.php/reumatologia/article/view/860

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